大学六级-1606及答案解析.doc
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1、大学六级-1606 及答案解析(总分:667.00,做题时间:90 分钟)一、Part Writing(总题数:1,分数:106.00)1.大学生刷信用卡消费已成普遍现象;2. 大学生过度使用信用卡可能带来哪些问题;3. 停止向大学生发放信用卡的理由和好处。(分数:106.00)_二、Part Reading Compr(总题数:1,分数:70.00)HIV 60 to 70% of those are in Sub-Saharan Africa. But the disease is spreading in every region, with fierce epidemics threa
2、tening to tear through countries such as India, China, Russia and the islands of the Caribbean. The statistics are sobering in some Southern African towns 44% of pregnant women are HIV positive, in Botswana 37% of people carry the virus.Immune assassinThe human immunodeficiency virus (HIV) is a retr
3、ovirusa virus built of RNA instead of more typical DNA. It attacks the very cells of the immune system that should be protecting the body against it F lymphocytes and other white blood cells with CD4 receptors on their surfaces. The virus uses the CD4 receptor to bind with and thereby enter the lymp
4、hocyte. HIV then integrates itself into the cells own DNA, turning the cell into a virus-generating factory. The new viruses break free, destroying the cell, then move on to attack other lymphocytes.HIV kills by slowly destroying the immune system. Several weeks after initial infection, flu-like sym
5、ptoms are experienced. Then the immune system kicks-in, and the virus mostly retreats into hiding within lymph tissues. The untreated, infected individual usually remains healthy for 5 to 15 years, but the virus continues to replicate in the background, slowly obliterating the immune system.Eventual
6、ly the body is unable to defend itself and succumbs to overwhelming opportunistic infections that rarely affect healthy people. Acquired Immune Deficiency Syndrome (AIDS) is the name given to this final stage of HIV infection, and is characterized by multiple, life-threatening illnesses such is weig
7、ht loss, chronic diarrheoa, rare cancers, pneumonia, fungal conditions and infections of the brain and eye. Tuberculosis has become especially prevalent in AIDS victims.Natural born killerGenetic analyses hint that ancestral primate HIV may have been born a million years ago when a chimpanzee virus
8、hybridized (杂交) with a related monkey variety. However researchers believe it was not until the 1930s that this jumped to humans eating chimp meat in Central Africa. That variety became HIV-1 the most widespread type. A second type, HIV-2, restricted to West Africa, was probably contracted in the 19
9、60s from monkey meat.Another theory was that the AIDS pandemic was accidentally started by doctors testing a polio vaccine in the 1950sdetailed in Edward Hoopers book The River but this has been severely criticized by other researchers.AIDS must have been circulating in the US and Africa during the
10、1970s. But it was not recognized until 1981 when young gay men and injecting drug users, in New York and California, started to be diagnosed with both an unusual skin cancer called Kaposis sarcoma, and lethal pneumonias. By the end of that year 121 people in the US had died that number would rise to
11、 17,000 over the next six years.Government scientists predicted that the mysterious immune-debilitating illness was due to an infectious agent. In 1984 that agent was identified as HIV by Luc Montagnier of the Pasteur Institute in Paris, France, and Robert Gallo of the National Cancer Institute in W
12、ashington DC, US.Soon after the appearance of AIDS in the US, the disease was detected in Europe too and epidemics affecting heterosexual men and women sprang up at an alarming rate in Sub-Saharan Africa. Today one in five people in that region are living with the virus. AIDS epidemics also threaten
13、 to devastate the worlds most populous nations India and China if action is not taken to bring them under control. Defensive measuresHIV is found in body fluids such as: blood, semen, vaginal fluids and breast milk. It can be passed on through penetrative sex, oral sex and sharing contaminated needl
14、es when injecting street drugs or in hospitals. It can also be transmitted from a mother to her baby during pregnancy, childbirth or breastfeeding though many children escape infection. HIV cannot be passed on through kissing, coughing, mosquito bites or touching.Health authorities are focusing on p
15、revention as a key method to limit the spread of the epidemic. Educational programs preach abstinence from sex, monogamy and safer sex using condoms, as ways to protect against infection. Many countries give away free condoms and offer needle exchange programs to try and limit transmission among inj
16、ecting drug users. Microbicides in the form of creams that prevent transmission of HIV may soon offer another method of protection.A vaccine, as an alternative method to prevent HIV infection, may still be many years away. This is partly because the virus mutates so rapidly. A vaccine may not only h
17、ave to prime antibodies to attack the virus (the way most vaccines work) but might also need to increase T-cell production. Vaccine trial; have been undertaken in South Africa, Kenya, the US and Thailand though most have yet to yield promising results. Controversial vaccines made from the blood of H
18、IV carriers, have been tested is Nigeria and Thailand.Anti-retroviral cocktailsThere is no cure for AIDS, but a range of drugssome of which have unpleasant side-effectsare available to slow, its progress. Other drugs are used to treat opportunistic infections or AIDS symptoms. Even some herbal treat
19、ments have been investigated.Most anti-HIV drugs aim at stalling viral replication. Nucleoside analogues such as AZT (zidovudine) and also non-nucleoside reverse transcriptase inhibitors (NNRTIs) (非核苷类逆转录酶抑制剂), attack the action of the viral enzyme reverse transcriptase. This prevents it from creati
20、ng functional DNA which would otherwise integrate into the DNA of infected cells.A third class block protease, an enzyme essential for generating functional virus particles. Protease inhibitors are the most effective of the three types of drugs, and AIDS mortality fell dramatically in the US when th
21、ey were first licensed during the late 1990s. Fusion inhibitors are a newer type of drug that work by stopping HIV from binding with CD4 receptors that it uses to enter cells. Drugs that block another enzyme, integrase (整合酶), are also under development.AIDS drugs are often administered in combinatio
22、n cocktails of three or more kinds simultaneously, as this helps slow the rate at which HIV develops resistance to drugs. But the virus is able to evolve rapidly and can eventually outpace the drugs if treatment regimens are not followed rigorously.Though drugs are widely available in Western countr
23、ies, their expense means they are unavailable to the vast majority of AIDS sufferers. International bodies are working towards widening access to treatment in the developing world. Some companies in countries such as India and Thailand are now producing cheap generic copies of drugs.Staggering tollT
24、he economic and social burden of AIDS exerts a great toll on developing nations in addition to that exerted by mortality itself. AIDS is hindering development and leading to negative population growth in some of the most seriously affected nations, such as Botswana.This excessive AIDS mortality is c
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