BS DD ISO TS 17924-2008 Soil quality - Assessment of human exposure from ingestion of soil and soil material - Guidance on the application and selection of physiologically based ex.pdf
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1、DRAFT FOR DEVELOPMENTDD ISO/TS 17924:2007Soil quality Assessment of human exposure from ingestion of soil and soil material Guidance on the application and selection of physiologically based extraction methods for the estimation of the human bioaccessibility/ bioavailability of metals in soilICS 13.
2、080.30g49g50g3g38g50g51g60g44g49g42g3g58g44g55g43g50g56g55g3g37g54g44g3g51g40g53g48g44g54g54g44g50g49g3g40g59g38g40g51g55g3g36g54g3g51g40g53g48g44g55g55g40g39g3g37g60g3g38g50g51g60g53g44g42g43g55g3g47g36g58DD ISO/TS 17924:2007This Draft for Development was published under the authority of the Standa
3、rds Policy and Strategy Committee on 29 February 2008 BSI 2008ISBN 978 0 580 53132 3National forewordThis Draft for Development is the UK implementation of ISO/TS 17924:2007.This publication is not to be regarded as a British Standard.It is being issued in the Draft for Development series of publica
4、tions and is of a provisional nature. It should be applied on this provisional basis, so that information and experience of its practical application can be obtained.Comments arising from the use of this Draft for Development are requested so that UK experience can be reported to the international o
5、rganization responsible for its conversion to an international standard. A review of this publication will be initiated not later than three years after its publication by the international organization so that a decision can be taken on its status. Notification of the start of the review period wil
6、l be made in an announcement in the appropriate issue of Update Standards.According to the replies received by the end of the review period, the responsible BSI Committee will decide whether to support the conversion into an international Standard, to extend the life of the Technical Specification o
7、r to withdraw it. Comments should be sent to the Secretary of the responsible BSI Technical Committee at British Standards House, 389 Chiswick High Road, London W4 4AL.The UK participation in its preparation was entrusted to Technical Committee EH/4, Soil quality.A list of organizations represented
8、on this committee can be obtained on request to its secretary.This publication does not purport to include all the necessary provisions of a contract. Users are responsible for its correct application.Amendments/corrigenda issued since publicationDate CommentsReference numberISO/TS 17924:2007(E)TECH
9、NICAL SPECIFICATION ISO/TS17924First edition2007-12-15Soil quality Assessment of human exposure from ingestion of soil and soil material Guidance on the application and selection of physiologically based extraction methods for the estimation of the human bioaccessibility/bioavailability of metals in
10、 soil Qualit du sol valuation de lexposition humaine par ingestion de sol et de matriaux du sol Lignes directrices pour lapplication et la slection de mthodes dextraction fondes sur le point de vue physiologique pour lestimation de la bioaccessibilit/biodisponibilit pour ltre humain de mtaux dans le
11、 sol DD ISO/TS 17924:2007ii iiiContents Page Foreword iv Introduction v 1 Scope . 1 2 Normative references . 1 3 Terms and definitions. 1 4 Bioaccessibility/bioavailability as a concept in assessment of soils and sites with respect to human exposure. 3 5 Description of the mechanisms of human contam
12、inant uptake 5 6 Description of metal-binding mechanisms (speciation of metals) in soil 8 7 Concept for a method to test the bioavailability through human exposure. 8 7.1 General. 8 7.2 Choosing an appropriate test 9 7.3 Description of applicable test methods 11 7.4 Recommendations 12 7.5 Use and in
13、terpretation of in vitro tests for risk assessment 13 8 Data handling, quality control and presentation of results 14 Annex A (informative) Human bioaccessibility testing 15 DD ISO/TS 17924:2007iv Foreword ISO (the International Organization for Standardization) is a worldwide federation of national
14、 standards bodies (ISO member bodies). The work of preparing International Standards is normally carried out through ISO technical committees. Each member body interested in a subject for which a technical committee has been established has the right to be represented on that committee. Internationa
15、l organizations, governmental and non-governmental, in liaison with ISO, also take part in the work. ISO collaborates closely with the International Electrotechnical Commission (IEC) on all matters of electrotechnical standardization. International Standards are drafted in accordance with the rules
16、given in the ISO/IEC Directives, Part 2. The main task of technical committees is to prepare International Standards. Draft International Standards adopted by the technical committees are circulated to the member bodies for voting. Publication as an International Standard requires approval by at lea
17、st 75 % of the member bodies casting a vote. In other circumstances, particularly when there is an urgent market requirement for such documents, a technical committee may decide to publish other types of document: an ISO Publicly Available Specification (ISO/PAS) represents an agreement between tech
18、nical experts in an ISO working group and is accepted for publication if it is approved by more than 50 % of the members of the parent committee casting a vote; an ISO Technical Specification (ISO/TS) represents an agreement between the members of a technical committee and is accepted for publicatio
19、n if it is approved by 2/3 of the members of the committee casting a vote. An ISO/PAS or ISO/TS is reviewed after three years in order to decide whether it will be confirmed for a further three years, revised to become an International Standard, or withdrawn. If the ISO/PAS or ISO/TS is confirmed, i
20、t is reviewed again after a further three years, at which time it must either be transformed into an International Standard or be withdrawn. Attention is drawn to the possibility that some of the elements of this document may be the subject of patent rights. ISO shall not be held responsible for ide
21、ntifying any or all such patent rights. ISO/TS 17924 was prepared by Technical Committee ISO/TC 190, Soil quality, Subcommittee SC 7, Soil and site assessment. DD ISO/TS 17924:2007vIntroduction When assessing soils contaminated with, for example, metals, soil ingestion, especially by children, is of
22、ten considered to be the most important exposure pathway. Currently, this assessment is often carried out on the basis of the total content of the metals in question in the soil. However, several studies suggest that the availability of the metals in the gastrointestinal tract is dependent on the fo
23、rm of the metals present and the site-specific soil chemistry. Test methods based on in vivo tests with, for example, juvenile swine or mini-pigs are time consuming and expensive, and not very compatible with the decision processes connected with the assessment and clean-up of contaminated sites. At
24、 present, test methods are being developed and validated, which involve in vitro laboratory tests aimed at simulating in vivo results. This will reduce the cost and practicalities related to the use of such testing on contaminated land. Due to the large expenditure necessary for both private landown
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