[外语类试卷]大学英语六级模拟试卷384及答案与解析.doc
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1、大学英语六级模拟试卷 384及答案与解析 一、 Part I Writing (30 minutes) 1 Directions: In this part, you are allowed 30 minutes to write a short essay entitled An Eye-witness Account of a Traffic Accident. You should write at least 150 words following the outline given below. 1. 车祸发生的时间及地点; 2你所见到的车祸情况; 3你对车祸原因的分析。 二、 Pa
2、rt II Reading Comprehension (Skimming and Scanning) (15 minutes) Directions: In this part, you will have 15 minutes to go over the passage quickly and answer the questions attached to the passage. For questions 1-4, mark: Y (for YES) if the statement agrees with the information given in the passage;
3、 N (for NO) if the statement contradicts the information given in the passage; NG (for NOT GIVEN) if the information is not given in the passage. 1 A Dose of Reality Major Reality Check When the pain reliever Vioxx was Withdrawn from the market last fall after the announcement that it increased pati
4、ents risk of heart attacks and strokes, millions of Americans panicked. The sometimes sensationalized headlines didnt help. People wondered, “Should I trust my doctor?“ “Could a medication that I thought would help me actually kill me?“ “Is our drug safety system broken?“ Suddenly, ads for the drug
5、were replaced with ads looking for Vioxx “victims“. Law firms across the nation began recruiting anyone who had ever taken the drug as plaintiffs (原告 ) for class-action (公诉 ) suits. Merck, the company that developed the drug, could be liable for billions of dollars, making it one of the costliest li
6、ability cases ever, No surprise, then, that Mercks stock plummeted(垂直落下 ) 40 percent in just six weeks. But the real cost was even greater. Not only did patients stop taking Vioxx but, doctors say, many people stopped taking their other medicines, toosometimes putting their health at serious risk. V
7、ioxx was the first pebble in the pharmaceutical rock slide. Soon, accusations about a spate of other drugs were making headlines, including all COX-2 inhibitors which, like Vioxx, relieve pain. The charges didnt stop there. The FDA was accused of simply robber-stamping new drugs; drug companies. wer
8、e blamed for hiding information about unsafe products; .and the efficacy(功效 ) of clinical trials that did not reveal how large numbers of people would react was questioned. But one question that was rarely asked could determine whether or not pharmaceutical companies continue to develop and produce
9、breakthrough medications that can save or extend lives and help people live without pain. The question: do Americans expect drugs to be risk-free? And, if someone suffers a bad reaction, will lawyers rather than doctors be the first people we call? Panic over Pills: Overreaction? During the ten-year
10、 period between 1994 and 2004, the FDA approved 321 completely new drugs (this doesnt include approvals for changes to existing medicines), bringing the total to more than 10,000 drug products on the market. During that same period, eight drugs were withdrawn for reasons of safety, such as the diet
11、drug fenfluramine (fen-phen, associated with heart-valve disease) and the allergy drug Seldane (linked to heart arrhythmias). But the Vioxx recall created a shock wave for the American consumer like no other. Many people had come to depend on their “meds“, and they expected them to be safe, too, esp
12、ecially when they cost so much. Prescription drugs account for, some Say, the fastest growing segment (about one- tenth) of all health expenditures, with some specialty drugs costing hundreds of dollars per dose. “With Vioxx, the real shock and outrage came when there was a suggestion that people in
13、 authority may have known about these harmful side effects and not shared them with doctors or the public,“ says Anne Woodbury, chief health advocate for the Center for Health Transformation, a think tank founded by Newt Gingrich. It made people question their faith in the pharmaceutical industry, f
14、ederal regulators and physiciansthose we trust to make sure our drugs are safe. Before, taking a newly prescribed pill with a slug of water was as routine as brushing your teeth. For many people, this is no longer the case. People have reason to worry. In clinical trial data submitted to the FDA, Vi
15、oxx showed no connection to heart problems. The drug was approved in May 1999. But after Vioxx hit the market and grew in popularity, heart problems were revealed lots of them. Tens of thousands of people may have been affected, and Merck was accused of hiding that information. “The system is not pe
16、rfect,“ comments Marianne J. Legato, MD, professor of clinical medicine at Columbia University College of Physicians and Surgeons in New York City. “Sometimes a company may not want to show data that are negative till they really know whats going on. But its ridiculous to suggest that they would sup
17、press things willy-nilly, because if a drug is going to cause severe side effects, its not in their best interest to hide that.“ How Side Effects Emerge How can dangerous side effects take years, or even decades, to become known? A new drug is first tested on animals. If the results indicate that it
18、s likely to be both safe and effective, the company applies to the FDA for permission to begin testing it in humans. Human studies have three phases: to evaluate safety, to determine effectiveness, end to verify safety, dosage and effectiveness. Although a trial may extend as long as five years and
19、often includes between 3,0DO and 10,000 people, each participant may only receive the medication for a period of weeks or months. Statistically, rare and dangerous side effects may not emerge until millions of people have used the drug, after FDA approval. So why dont we test drugs on more people an
20、d for longer periods of time? For one thing, quicker approvals may save lives, as with drugs for AIDS or a vaccine for a newly emerging flu pandemic. Another reason is cost. “It already costs a billion dollars to get a drag from an idea to the market,“ rays Corr. “If we had to study a million patien
21、ts before we took a drug to market, there would never be another drug.“ Monitoring after Approval After a drug is approved, it is subject to post-market surveillance(监督 ). The FDA analyzes reports of “adverse events“, or drug side effects, which come from the industry, from ongoing clinical trials a
22、nd through its Mad Watch program, to which consumers, physicians, pharmacists and other health professionals voluntarily report problems. Negative reports about a drug thats on the market can yield crucial new information. “Clinical trials that are negative are, many times, just as important as the
23、trials that show positive results,“ says Marvin Lipman, MD, chief medical adviser for Consumer Reports. Legislation was introduced in both the House and Senate in October 2004 to establish a registry of all clinical trials and their results. “We are the most regulated industry in the world,“ rays Co
24、rr. “And frankly, thats how it should be. If there is a problem with a drug, We want to know about it sooner rather than later.“ Consumers may know sooner too. In February the FDA announced the creation of an independent Drug Safety Oversight Board to provide expanded and faster drug-safety informat
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