[外语类试卷]专业英语八级模拟试卷363及答案与解析.doc
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1、专业英语八级模拟试卷 363及答案与解析 0 The FDA may rescind its approval of Avastin, a colon-cancer drug. If the summer of 2009 was the season of “death panels,“ as the debate over health-care reform exploded, this is the season of “17.5k dead women a year.“ Thats the body count scaremongers are predicting if the Fo
2、od and Drug Administration rescinds its provisional approval of the drug Avastin for metastatic breast cancer, a decision expected by years end. Although the move has nothing to do with the new health-care law, uncertainty about “Obama-care“ has given opponents an opening to terrify people about wha
3、ts cominglike bureaucrats rationing health care to save money. The reality is far different and, for those who care more about helping cancer patients than about scoring political points, much sadder. Thats because in 2008, when the FDA gave “fast track“ approval for Avastin in breast cancer that ha
4、s metastasizedusually to the lungs, bones, liver, or brainit was conditional on the manufacturer, Genentech, running additional clinical trials of the drugs safety and efficacy. There was good reason for that. Avastin is an angiogenesis inhibitor, a class of cancer drugs that have not lived up to th
5、eir hype: although they stop one mechanism by which malignant cells grow blood vessels to sustain them, the cells often activate a different mechanism and go on proliferating. Although Avastin does extend the lives of patients with metastatic colorectal and kidney cancer, and remains FDA-approved fo
6、r those uses, the new studies show it does not work the same miracle against metastatic breast cancer (MBC). Instead, Avastin increased whats called progression-free survival (how long before cancer spreads or grows) by about one to three weeks, depending on which chemo agent it was paired with. But
7、 it did not keep women alive any longer than chemo alone. To some advocates, progression-free survival without an increase in overall survival is still welcome, since it suggests patients have a better quality of life during their last months. But its hard to make that case for Avastin. Not only did
8、 it not keep women alive, but it also caused hypertension, hemorrhaging, bowel perforations, and other side effects. “It seems as if the drugs toxicity cancels out any benefit,“ cancer surgeon David Gorski of the Karmanos Cancer Institute told me. Perforated bowels do not equal a better quality of l
9、ife. These dismal results are what led an FDA panel to vote 121 in July to rescind the conditional approval of Avastin for MBC. Critics of health-care reform, predictably, saw nefarious motives-in particular, evidence that Obamacare will ration expensive drugs. (Avastin costs some $88,000 a year, th
10、ough few patients live that long.) The Wall Street Journal editorialized about the “Avastin mugging,“ and Sen. David Vitter accused the FDA of “assigning a value to a day of a persons life. “ If Avastin did extend lives for, lets say, $ 10,000 a day, Vitter might have a case. But it doesnt extend li
11、fe at all. That makes allegations like the 17,500 dead women (from a right-wing blog) “utter demagoguery of the most vile and despicable sort,“ Gorski wrote on the blog Science-Based Medicine. There are stories galore of women with metastatic breast cancer who are alive “because of Avastin. “ Indeed
12、, patients have been flooding the airwaves and blogosphere with claims that Avastin helped them. But the only way to tell whether Avastin deserves the credit for keeping patients alive is through large studies. “There are always patients who live longer than average,“ biostatistician Donald Berry of
13、 the MD? Anderson Cancer Center told me. “They attribute it to the treatment; people love to make attributions. “ But when the proportion of patients alive at any given time in a study is the same whether they are receiving Avastin or notas the two large trials foundthen crediting Avastin is “very l
14、ikely wrong. “ That some women did live longer on Avastin, Berry explained, “may simply reflect the natural heterogeneity of the disease and say nothing about the therapy. “ Doctors can keep prescribing Avastin for metastatic breast cancer off-label, though insurers will not pay for it. Some activis
15、ts welcome that. There is “no evidence of clinical benefit from Avastin, yet there is harm,“ says Fran Visco, president of the National Breast Cancer Coalition. “We need to demand more of treatment before we unleash it on the public. “ Science-based medicine isnt always pretty. But its better than p
16、olitics-based medicine, which is what some critics of the Avastin decision are practicingand much better than deluding ourselves into thinking something works when it doesnt. 1 What does “scaremonger“ mean in the second paragraph? ( A) A prophet who can predict what will happen in the future. ( B) A
17、 person who spreads frightening rumors and stirs up trouble. ( C) A scientist who is specialized in medicine. ( D) A sociologist who is concerned about social issues. 2 Which of the following is NOT the benefit of Avastin? ( A) It can help malignant cells grow blood vessels to sustain them. ( B) It
18、can extend the lives of patients with metastatic colorectal and kidney cancer. ( C) It can extend the lives of patients with breast cancer. ( D) It can help patients have a better quality of life during their last months. 3 Why may the FDA rescind its approval of Avastin? ( A) Because it may cause b
19、reast cancer to metastasize to other organs ( B) Because it did not keep women alive. ( C) Because it may cause side effects. ( D) Because its toxicity outweighs its benefits. 4 Opponents criticize FDAs rescinding its approval of Avastin because_. ( A) Avastin is too expensive ( B) they think Obama
20、will ration health care to save money ( C) few women benefit from the use of Avastin ( D) Avastin is effective in dealing with cancers 5 The best title of the passage is_. ( A) Its not about rationing ( B) Why the FDA may reverse course on Avastin ( C) A value to a day of a persons life ( D) Avastin
21、, a controversial medicine 5 I have a plan that will raise wages, lower prices, increase the nations stock of scientists and engineers, and maybe even create the next Google. Better yet, this plan wont cost the government a dime. In fact, it will save a lot of money. But few politicians are going to
22、 want to touch it. Heres the plan: More immigration. A pathway to legal status for undocumented immigrants. And a recognition that immigration policy is economic policy, and needs to be thought of as such. See what I meant about politicians not liking it? Economists will tell you that immigrants rai
23、se wages for the average native-born worker. Theyll tell you that they make things cheaper for us to buy here, and that if we didnt have immigrants for some of these jobs, the jobs would move to other countries. Theyll tell you that we should allow for much more highly skilled immigration, because t
24、hats about as close to a free lunch as youre likely to find. Theyll tell you that the people who should most want a path to legal status for undocumented immigrants are the low-income workers who are most opposed to such plans. And about all this, the economists are right. There are also noneconomic
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- 外语类 试卷 专业 英语 模拟 363 答案 解析 DOC
